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IRAC group 23

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By Targets:	Biochemical Assay Reagents (2) Drug Intermediate (2) Drug Metabolite (1) Endogenous Metabolite (2) Insecticide (1) Isotope-Labeled Compounds (1) Reference Standards (1)

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Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: HMG Family

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N2436

2,3-Dihydroxysuccinic acid Tartaric acid	Biochemical Assay Reagents	Others
2,3-Dihydroxysuccinic acid (Tartaric acid) is an organic acid containing two hydroxyl groups and two carboxyl groups. 2,3-Dihydroxysuccinic acid exists in various stereoisomers and is widely used in food, pharmaceutical, chemical, and other fields .

HY-114296

2,3-Oxidosqualene Squalene oxide	Drug Intermediate Endogenous Metabolite	Others
2,3-Oxidosqualene (Squalene oxide) is a sterol biosynthesis precursor intermediate.2,3-Oxidosqualene participates in cyclization pathways that form sterols and triterpenes, and contributes to introduction of their characteristic 3-hydroxyl group.2,3-Oxidosqualene forms metabolically from squalene in rat liver homogenates under sterol synthesis conditions.2,3-Oxidosqualene converts to sterols including cholesterol, lathosterol, and lanost-8-en-3β-ol in rat liver homogenates under anaerobic conditions .

HY-164322

Cyproflanilide	Insecticide	Others
Cyproflanilide is a meta-diamide insecticide. Cyproflanilide exhibits potent insecticidal activity against third Chilo suppressalis and Spodoptera frugiperda larvae. Cyproflanilide can be used for the research of insect pests .

HY-N2436R

2,3-Dihydroxysuccinic acid (Standard) Tartaric acid (Standard)	Biochemical Assay Reagents Reference Standards	Others
2,3-Dihydroxysuccinic acid (Standard) (Tartaric acid (Standard)) is the analytical standard of 2,3-Dihydroxysuccinic acid (HY-N2436). This product is intended for research and analytical applications. 2,3-Dihydroxysuccinic acid (Tartaric acid) is an organic acid containing two hydroxyl groups and two carboxyl groups. 2,3-Dihydroxysuccinic acid exists in various stereoisomers and is widely used in food, pharmaceutical, chemical, and other fields.

HY-114296S

2,3-Oxidosqualene-d6 Squalene oxide-d₆	Isotope-Labeled Compounds Drug Intermediate Endogenous Metabolite	Others
2,3-Oxidosqualene-d₆ (Squalene oxide-d₆) is a deuterium labeled 2,3-Oxidosqualene (HY-114296). 2,3-Oxidosqualene (Squalene oxide) is a sterol biosynthesis precursor intermediate.2,3-Oxidosqualene participates in cyclization pathways that form sterols and triterpenes, and contributes to introduction of their characteristic 3-hydroxyl group.2,3-Oxidosqualene forms metabolically from squalene in rat liver homogenates under sterol synthesis conditions.2,3-Oxidosqualene converts to sterols including cholesterol, lathosterol, and lanost-8-en-3β-ol in rat liver homogenates under anaerobic conditions.

HY-W714238

Spirotetramat-mono-hydroxy	Drug Metabolite	Others
Spirotetramat-mono-hydroxy is a metabolite of Spirotetramat (HY-120253). Spirotetramat is an insecticide .

Cat. No.	Product Name	Type

HY-N2436

2,3-Dihydroxysuccinic acid Tartaric acid	Biochemical Assay Reagents
2,3-Dihydroxysuccinic acid (Tartaric acid) is an organic acid containing two hydroxyl groups and two carboxyl groups. 2,3-Dihydroxysuccinic acid exists in various stereoisomers and is widely used in food, pharmaceutical, chemical, and other fields .

HY-N2436R

2,3-Dihydroxysuccinic acid (Standard) Tartaric acid (Standard)	Biochemical Assay Reagents
2,3-Dihydroxysuccinic acid (Standard) (Tartaric acid (Standard)) is the analytical standard of 2,3-Dihydroxysuccinic acid (HY-N2436). This product is intended for research and analytical applications. 2,3-Dihydroxysuccinic acid (Tartaric acid) is an organic acid containing two hydroxyl groups and two carboxyl groups. 2,3-Dihydroxysuccinic acid exists in various stereoisomers and is widely used in food, pharmaceutical, chemical, and other fields.

2,3-Dihydroxysuccinic acid (Standard)

Tartaric acid (Standard)

Biochemical Assay Reagents

2,3-Dihydroxysuccinic acid (Standard) (Tartaric acid (Standard)) is the analytical standard of 2,3-Dihydroxysuccinic acid (HY-N2436). This product is intended for research and analytical applications. 2,3-Dihydroxysuccinic acid (Tartaric acid) is an organic acid containing two hydroxyl groups and two carboxyl groups. 2,3-Dihydroxysuccinic acid exists in various stereoisomers and is widely used in food, pharmaceutical, chemical, and other fields.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N2436

2,3-Dihydroxysuccinic acid Tartaric acid	Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Biochemical Assay Reagents
2,3-Dihydroxysuccinic acid (Tartaric acid) is an organic acid containing two hydroxyl groups and two carboxyl groups. 2,3-Dihydroxysuccinic acid exists in various stereoisomers and is widely used in food, pharmaceutical, chemical, and other fields .

HY-N2436R

2,3-Dihydroxysuccinic acid (Standard) Tartaric acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Biochemical Assay Reagents Reference Standards
2,3-Dihydroxysuccinic acid (Standard) (Tartaric acid (Standard)) is the analytical standard of 2,3-Dihydroxysuccinic acid (HY-N2436). This product is intended for research and analytical applications. 2,3-Dihydroxysuccinic acid (Tartaric acid) is an organic acid containing two hydroxyl groups and two carboxyl groups. 2,3-Dihydroxysuccinic acid exists in various stereoisomers and is widely used in food, pharmaceutical, chemical, and other fields.

Cat. No.	Product Name	Chemical Structure

HY-114296S

2,3-Oxidosqualene-d6
2,3-Oxidosqualene-d₆ (Squalene oxide-d₆) is a deuterium labeled 2,3-Oxidosqualene (HY-114296). 2,3-Oxidosqualene (Squalene oxide) is a sterol biosynthesis precursor intermediate.2,3-Oxidosqualene participates in cyclization pathways that form sterols and triterpenes, and contributes to introduction of their characteristic 3-hydroxyl group.2,3-Oxidosqualene forms metabolically from squalene in rat liver homogenates under sterol synthesis conditions.2,3-Oxidosqualene converts to sterols including cholesterol, lathosterol, and lanost-8-en-3β-ol in rat liver homogenates under anaerobic conditions.

2,3-Oxidosqualene-d6

2,3-Oxidosqualene-d₆ (Squalene oxide-d₆) is a deuterium labeled 2,3-Oxidosqualene (HY-114296). 2,3-Oxidosqualene (Squalene oxide) is a sterol biosynthesis precursor intermediate.2,3-Oxidosqualene participates in cyclization pathways that form sterols and triterpenes, and contributes to introduction of their characteristic 3-hydroxyl group.2,3-Oxidosqualene forms metabolically from squalene in rat liver homogenates under sterol synthesis conditions.2,3-Oxidosqualene converts to sterols including cholesterol, lathosterol, and lanost-8-en-3β-ol in rat liver homogenates under anaerobic conditions.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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IRAC group 23

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Natural
Products