2,3-Dihydroxysuccinic acid
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2,3-Dihydroxysuccinic acid (Tartaric acid) is an organic acid containing two hydroxyl groups and two carboxyl groups. 2,3-Dihydroxysuccinic acid exists in various stereoisomers and is widely used in food, pharmaceutical, chemical, and other fields.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 526-83-0
- Formula: C4H6O6
- Molecular Weight:150.09
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
2,3-Dihydroxysuccinic acid can be derived from ascorbic acid metabolism in grapes. As a major organic acid, it accumulates in vacuoles, influencing the acidity and aging characteristics of wine. Its biosynthesis and functions involve multiple aspects such as enzymatic regulation, osmotic adjustment, and oxidative stress response[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 526-83-0
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Appearance Solid
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Molecular Weight 150.09
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Formula C4H6O6
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Color White to off-white
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SMILES
O=C(C(C(C(O)=O)O)O)O
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Synonyms
Tartaric acid
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (666.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Fang SM, et al. From infinite one-dimensional helix to discrete Cu(II)15 cluster along with in situ S(N)2 ring-cleavage of cis-epoxysuccinic acid: pH-controlled assemblies, crystal structures, and properties. Inorg Chem. 2010 Oct 18;49(20):9617-26. [Content Brief]
[2]. Burbidge CA, et al. Biosynthesis and Cellular Functions of Tartaric Acid in Grapevines. Front Plant Sci. 2021 Mar 4;12:643024. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.6627 mL | 33.3133 mL | 66.6267 mL | 166.5667 mL |
| 5 mM | 1.3325 mL | 6.6627 mL | 13.3253 mL | 33.3133 mL | |
| 10 mM | 0.6663 mL | 3.3313 mL | 6.6627 mL | 16.6567 mL | |
| 15 mM | 0.4442 mL | 2.2209 mL | 4.4418 mL | 11.1044 mL | |
| 20 mM | 0.3331 mL | 1.6657 mL | 3.3313 mL | 8.3283 mL | |
| 25 mM | 0.2665 mL | 1.3325 mL | 2.6651 mL | 6.6627 mL | |
| 30 mM | 0.2221 mL | 1.1104 mL | 2.2209 mL | 5.5522 mL | |
| 40 mM | 0.1666 mL | 0.8328 mL | 1.6657 mL | 4.1642 mL | |
| 50 mM | 0.1333 mL | 0.6663 mL | 1.3325 mL | 3.3313 mL | |
| 60 mM | 0.1110 mL | 0.5552 mL | 1.1104 mL | 2.7761 mL | |
| 80 mM | 0.0833 mL | 0.4164 mL | 0.8328 mL | 2.0821 mL | |
| 100 mM | 0.0666 mL | 0.3331 mL | 0.6663 mL | 1.6657 mL |