1 Result for "

ISM7594

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ISM7594" in MCE Product Catalog:

Cat. No.: HY-174974
CAS No.: 3025799-76-9
Target:  

FGFR

Research Areas:  

Cancer

ISM7594 is an orally active FGFR2/3 inhibitor. ISM7594 shows broad-spectrum antiproliferative potency in FGFR2- or FGFR3-altered cancer cell panels, including FGFR2/3 amplification, fusion, and mutation (BaF3-TEL-FGFR2-V564F (IC50 = 0.067 nM), BaF3-TEL-FGFR2-V564I (IC50 = 2 nM)) types. ISM7594 inhibits tumor growth in a dose-dependent manner. ISM7594 can be used for the study of advanced solid tumors with FGFR2/3 aberrations .
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