2 Results for "

JK-P3

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "JK-P3" in MCE Product Catalog:

Cat. No.: HY-108933
CAS No.: 942655-44-9
Purity:  99.72%
Target:  

VEGFR FGFR

Research Areas:  

Cancer

JK-P3 is a potent and pan VEGFR2 inhibitor, with IC50s of 7.83 μM, 27 μM and 5.18 μM for VEGFR2, FGFR1 and FGFR3, respectively. JK-P3 can inhibit VEGF-A-stimulated VEGFR2 activation and intracellular signalling, also inhibits endothelial monolayer wound closure and angiogenesis, as well as fibroblast growth factor receptor kinase activity in vitro. JK-P3 has anti-angiogenic activity .
loading...
    loading...
Cat. No.: HY-108933R
CAS No.: 942655-44-9
Research Areas:  

Cancer

JK-P3 (Standard) is the analytical standard of JK-P3 (HY-108933). This product is intended for research and analytical applications. JK-P3 is a potent and pan VEGFR2 inhibitor, with IC50s of 7.83 μM, 27 μM and 5.18 μM for VEGFR2, FGFR1 and FGFR3, respectively. JK-P3 can inhibit VEGF-A-stimulated VEGFR2 activation and intracellular signalling, also inhibits endothelial monolayer wound closure and angiogenesis, as well as fibroblast growth factor receptor Kinase activity in vitro. JK-P3 has anti-angiogenic activity .
loading...
    loading...