1 Result for "

JNJ711

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "JNJ711" in MCE Product Catalog:

Cat. No.: HY-P992395
Synonyms: JNJ-711

Target:  

TNF Receptor NF-κB

Research Areas:  

Cancer

JNJ-64164711 (JNJ-711) is a bifunctional antibody that simultaneously targets human GITR/TNFRSF18 and FcγRIIIa. JNJ-64164711 binds to the GITR domain to activate the NF-κB signaling pathway, while binding to FcγRIIIa to support antibody-dependent cellular cytotoxicity (ADCC). JNJ-64164711 can specifically eliminate GITR-positive hematological tumor cells, activated T cells and intratumoral regulatory T cells through the ADCC mechanism, thereby significantly enhancing the body's anti-tumor immune response. JNJ-64164711 can be used in research related to non-small cell lung cancer, colorectal cancer, prostate cancer, renal cell carcinoma and hematological tumors .
loading...
    loading...