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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
JURKAT-eDHFR-YFP cells
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "JURKAT-eDHFR-YFP cells" in MCE Product Catalog:
Research Areas:
PROTAC eDHFR Degrader-1 is a PROTAC eDHFR degrader. PROTAC eDHFR Degrader-1 binds eDHFR-tagged proteins and Cereblon, thereby driving ternary complex formation, ubiquitination and proteasomal degradation. PROTAC eDHFR Degrader-1 degrades eDHFR-tagged proteins in multiple cell types and rodent models, and enables multiplex orthogonal protein regulation. PROTAC eDHFR Degrader-1 can be used in research related to metastatic ovarian cancer .
Cat. No.: HY-149679
CAS No.: 2849442-91-5
Research Areas:
PROTAC eDHFR Degrader-2 is a PROTAC degrader targeting eDHFR. PROTAC eDHFR Degrader-2 promotes the formation of a ternary complex between eDHFR-tagged proteins and the E3 ligase Cereblon, driving ubiquitin-proteasome-mediated degradation. PROTAC eDHFR Degrader-2 downregulates eDHFR-YFP in lymphoid cells and embryonic kidney cells. PROTAC eDHFR Degrader-2 can be used in studies related to metastatic ovarian cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
