1 Result for "

K-Ras(M72C)

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "K-Ras(M72C)" in MCE Product Catalog:

Cat. No.: HY-114894
CAS No.: 2230185-95-0
Target:  

Ras PI3K SOS1

Research Areas:  

Cancer

2C07 is a mutant Ras (K-Ras M72C, H-Ras M72C) inhibitor. 2C07 blocks the activation of PI3K through allosteric Ras modification. 2C07 binds to the modified switch II pocket (S-IIG) of Ras in both GDP- and GTP-bound states, stabilizes the GDP-bound state, disrupts the polar interactions of the canonical GTP-bound state, and inhibits SOS binding and nucleotide exchange. 2C07 can be used in cancer-related research .
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