1 Result for "

KN 62

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KN 62" in MCE Product Catalog:

13
13 Cited Publications
Cat. No.: HY-13290
CAS No.: 127191-97-3
Purity:  99.45%
Target:  

CaMK P2X Receptor

Research Areas:  

Metabolic Disease Cancer

KN-62 is a selective and reversible inhibitor of calmodulin-dependent protein kinase II (CaMK-II) with a Ki of 0.9 μM for rat brain CaMK-II. KN-62 directly binds to the calmodulin binding site of CaMK-II. KN-62 displays noncompetitive antagonism at P2X7 receptors in HEK293 cells, with an IC50 value of approximately 15 nM.
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