1 Result for "

L-PCPA

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "L-PCPA" in MCE Product Catalog:

4-Chloro-L-phenylalanine
4-Chloro-L-phenylalanine
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Cat. No.: HY-W019599
CAS No.: 14173-39-8
Synonyms: L-PCPA
Target:  

5-HT Receptor Tryptophan Hydroxylase

Research Areas:  

Neurological Disease

4-Chloro-L-phenylalanine (L-PCPA) is a tryptophan hydroxylase inhibitor targeting TPH1 and TPH2, with the activity of blocking serotonin biosynthesis. 4-Chloro-L-phenylalanine reduces the levels of serotonin and its metabolites in the brain without impairing the survival of serotonergic neurons. 4-Chloro-L-phenylalanine enhances anhedonic, depression-like and anxiety-like behaviors in mice with depleted noradrenergic and dopaminergic neurons. 4-Chloro-L-phenylalanine acts as a decarboxylation substrate for aromatic L-amino acid decarboxylase from Bacillus atrophaeus. 4-Chloro-L-phenylalanine can be used in studies related to Parkinson's disease .
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