1 Result for "

LM4108

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "LM4108" in MCE Product Catalog:

Cat. No.: HY-123639
CAS No.: 261766-32-9
Synonyms: N-(2-Phenylethyl)-indomethacin amide
Target:  

COX

Research Areas:  

Inflammation/Immunology Cancer

LM-4108 (N-(2-Phenylethyl)-indomethacin amide) is a selective and orally active COX-2 inhibitor with an IC50 of 0.06 μM for purified human COX-2. LM-4108 shows anti-inflammatory activity and may be effective in prevention of cancer. Half-lives for the disappearance of 10 μM LM-4108 in rat, human, and mouse liver microsomes were 11 min, 21 min, and 51 min, respectively .
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