5 Results for "

LNA-A

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "LNA-A" in MCE Product Catalog:

Cat. No.: HY-W406070
CAS No.: 207131-16-6
Synonyms: LNA-G
2′-O,4′-C-Methyleneguanosine (LNA-G) is a reverse guanine analog, where LNA (locked nucleic acid) is a nucleic acid analog. LNA modification can be widely used in various fields, such as effective binding affinity with complementary sequences and stronger nuclease resistance than natural nucleotides, providing great potential for application in disease diagnosis and research. 2'-O,4'-C-Methyleneguanosine is a substrate for KOD DNA polymerase, which incorporates LNA-G nucleotides into growing DNA strands, including consecutive incorporations , to generate full-length extension products .
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Cat. No.: HY-110407
CAS No.: 206055-70-1
Purity:  96.96%
Synonyms: LNA-A
2'-O,4'-C-Methyleneadenosine (LNA-A) is a locked nucleic acid (LNA) and is also an adenosine analog .
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Cat. No.: HY-176806
CAS No.: 606967-53-7
Synonyms: Doxorubicin-LNAA-Boc
Target:  

Drug Derivative

Research Areas:  

Cancer

Legubicin (Doxorubicin-LNAA-Boc) is a novel conjugate of Doxorubicin (HY-15142A) and a Legumain-cleavable peptide linker. Legubicin is activated by Legumain to release leucine-doxorubicin while sparing normal tissues. Legubicin inhibits tumor cell growth and reduces DNA binding in non-legumain expressing cells. Legubicin completely arrests tumor growth in mice bearing CT26 tumors. Legubicin can be used for the study of colon carcinoma (CRC) .
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Cat. No.: HY-W570887
CAS No.: 206055-79-0
LNA-A (Bz) amidite is a phosphoramidite monomer applicable for oligonucleotide synthesis, such as the synthesis of miniature LNA anti-miRNA-122 antisense oligonucleotides .
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Cat. No.: HY-110407R
CAS No.: 206055-70-1
Synonyms: LNA-A (Standard)
2'-O,4'-C-Methyleneadenosine (Standard) is the analytical standard of 2'-O,4'-C-Methyleneadenosine (HY-110407). This product is intended for research and analytical applications. 2'-O,4'-C-Methyleneadenosine (LNA-A) is a locked nucleic acid (LNA) and is also an adenosine analog .
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