1 Result for "

LSD1-IN-38

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "LSD1-IN-38" in MCE Product Catalog:

Cat. No.: HY-170403
Target:  

Histone Demethylase

Research Areas:  

Cancer

LSD1-IN-38 (Compound 23e) is a reversible, orally active inhibitor for lysine specific demethylase 1 (LSD1) with an IC50 of 1.2 nM. LSD1-IN-38 inhibits the proliferation of cancer cells MV4-11, Kasumi-1 and NCI-H526, with IC50 of 5, 4 and 11 nM, respectively. LSD1-IN-38 activates CD86 expression with an EC50 of 0.034 μM, and induces differentiation in MV4−11 cell. LSD1-IN-38 exhibits antitumor efficacy in mouse models .
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