1 Result for "

Lonaprisan

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Lonaprisan" in MCE Product Catalog:

Cat. No.: HY-16290
CAS No.: 211254-73-8
Synonyms: ZK 230211; BAY86 5044
Target:  

Progesterone Receptor

Research Areas:  

Endocrinology

Lonaprisan (ZK 230211; BAY86 5044) is an antagonist for progesterone receptor, with IC50 of 3.6 pM and 2.5 pM for PR-A and PR-B, respectively. Lonaprisan exhibits antiprogestagenic activity in rabbits, interrupts early pregnancy in rats, and exhibits antitumor efficacy against DMBA (HY-W011845)-induced mammary tumor. Lonaprisan reveals antiglucocorticoid and antiandrogenic effect .
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