2 Results for "

M 3554

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "M 3554" in MCE Product Catalog:

Cat. No.: HY-158109
Purity:  99.39%
M3554 is an anti-GD2 antibody-drug conjugate (ADC) based on the humanized anti-GD2 antibody. M3554 consists of the humanized monoclonal antibody hu14.18 (K322A) (HY-P991040) linked to a topoisomerase 1 inhibitor Exatecan (HY-13631) via a cleavable β-glucuronide linker. M3554 can be used for the study of neuroblastoma, osteosarcoma or glioma .
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Cat. No.: HY-P991040
Synonyms: Gamsitabart; M3554 Antibody

Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

hu14.18 (K322A) is a humanized anti-disialoganglioside GD2 monoclonal antibody that contains fully human amino acid sequences for immunoglobulin G1 heavy and kappa light chains. hu14.18 (K322A) has antibody-dependent cellular cytotoxicity (ADCC). hu14.18 (K322A) can be used for the study of high-risk neuroblastoma .
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