4 Results for "

MB-COMT

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "MB-COMT" in MCE Product Catalog:

Cat. No.: HY-E70007
CAS No.: 9012-25-3
Synonyms: COMT
Catechol O-methyltransferase, porcine liver (COMT), the magnesium-dependent transfer of methyl groups from S-adenosyl methionine to a hydroxyl group on dopamine, converting it to 3-methoxytyramine. Catechol O-methyltransferase has two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). Catechol O-methyltransferase is to regulate epinephrine, norepinephrine, and dopamine levels in the brain .
loading...
    loading...
Cat. No.: HY-151388
CAS No.: 254974-70-4
Purity:  98.04%
Target:  

Monoamine Oxidase COMT

Research Areas:  

Neurological Disease

hMAO-B/MB-COMT-IN-1 is a dual MAO-B/MB-COMT inhibitor (IC50s: 2.5 μΜ for hMAO-B, 3.84 μΜ for MB-COMT). hMAO-B/MB-COMT-IN-1 protects cells against oxidative damage. hMAO-B/MB-COMT-IN-1 can be used in the research of neurodegeneration disease, such as Parkinson’s Disease (PD) .
loading...
    loading...
Cat. No.: HY-151390
CAS No.: 3033106-46-3
Target:  

Monoamine Oxidase COMT

Research Areas:  

Neurological Disease

hMAO-B/MB-COMT-IN-2 is a dual MAO-B/MB-COMT inhibitor (IC50s: 4.27 μΜ for hMAO-B, 2.69 μΜ for MB-COMT). hMAO-B/MB-COMT-IN-2 protects cells against oxidative damage. hMAO-B/MB-COMT-IN-2 can be used in the research of neurodegeneration disease, such as Parkinson’s Disease (PD) .
loading...
    loading...
Cat. No.: HY-168154
Target:  

COMT

Research Areas:  

Cancer

COMT-IN-2 (compund 9) is the potent COMT inhibitor, showing selective inhibition of brain (IC50=24 nM) and liver (IC50=81 nM) MB-COMT compared to the liver S-COMT (IC50=620 nM) isoform .
loading...
    loading...