3033106-46-3
Chemical Structure
hMAO-B/MB-COMT-IN-2
- CAS No.: 3033106-46-3
- Formula:C17H18N2O3
- Molecular Weight:298.34
IUPAC Name: (2Z,4E)-5-(3,4-dihydroxyphenyl)-2-(piperidine-1-carbonyl)penta-2,4-dienenitrile
InChIKey: AURKHVWGDUMMNB-VJDVQFHISA-N
SMILES: OC1=CC(/C=C/C=C(C#N)\C(N2CCCCC2)=O)=CC=C1O
Biological Activity: hMAO-B/MB-COMT-IN-2 is a dual MAO-B/MB-COMT inhibitor (IC50s: 4.27 μΜ for hMAO-B, 2.69 μΜ for MB-COMT). hMAO-B/MB-COMT-IN-2 protects cells against oxidative damage. hMAO-B/MB-COMT-IN-2 can be used in the research of neurodegeneration disease, such as Parkinson’s Disease (PD)[1].
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hMAO-B/MB-COMT-IN-2 | hMAO-B/MB-COMT-IN-2 is a dual MAO-B/MB-COMT inhibitor (IC50s: 4.27 μΜ for hMAO-B, 2.69 μΜ for MB-COMT). hMAO-B/MB-COMT-IN-2 protects cells against oxidative damage. hMAO-B/MB-COMT-IN-2 can be used in the research of neurodegeneration disease, such as Parkinson’s Disease (PD). | |||||||||||||||||||||
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Keywords