3 Results for "

MGCD265

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "MGCD265" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-19642A
CAS No.: 2319837-80-2
Synonyms: MGCD265 hydrochloride
Target:  

TAM Receptor c-Met/HGFR

Research Areas:  

Cancer

Glesatinib hydrochloride (MGCD265 hydrochloride) is an orally active, potent MET/SMO dual inhibitor. Glesatinib hydrochloride, a tyrosine kinase inhibitor, antagonizes P-glycoprotein (P-gp) mediated multidrug resistance (MDR) in non-small cell lung cancer (NSCLC) .
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Cat. No.: HY-10991
CAS No.: 875337-44-3
Purity:  98.49%
Target:  

c-Met/HGFR VEGFR Apoptosis

Research Areas:  

Cancer

MGCD-265 analog is a potent and oral active inhibitor of c-Met and VEGFR2 tyrosine kinases, with IC50s of 29 nM and 10 nM, respectively. MGCD-265 analog has significant antitumor activity .
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Cat. No.: HY-19642
CAS No.: 936694-12-1
Synonyms: MGCD265
Target:  

TAM Receptor c-Met/HGFR

Research Areas:  

Cancer

Glesatinib (MGCD265) is an orally active, potent MET/SMO dual inhibitor. Glesatinib, a tyrosine kinase inhibitor, antagonizes P-glycoprotein (P-gp) mediated multidrug resistance (MDR) in non-small cell lung cancer (NSCLC) .
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