875337-44-3
875337-44-3
Chemical Structure
MGCD-265 analog
- CAS No.: 875337-44-3
- Formula:C26H20FN5O2S2
- Molecular Weight:517.60
IUPAC Name: N-((3-fluoro-4-((2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yl)oxy)phenyl)carbamothioyl)-2-phenylacetamide
InChIKey: UFICVEHDQUKCEA-UHFFFAOYSA-N
SMILES: O=C(CC1=CC=CC=C1)NC(NC2=CC=C(C(F)=C2)OC3=C4C(C=C(S4)C5=CN(C=N5)C)=NC=C3)=S
Biological Activity: MGCD-265 analog is a potent and oral active inhibitor of c-Met and VEGFR2 tyrosine kinases, with IC50s of 29 nM and 10 nM, respectively. MGCD-265 analog has significant antitumor activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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MGCD-265 analog | 98.49% | MGCD-265 analog is a potent and oral active inhibitor of c-Met and VEGFR2 tyrosine kinases, with IC50s of 29 nM and 10 nM, respectively. MGCD-265 analog has significant antitumor activity. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.70
HY-19642Glesatinib -
Similarity Score 0.69
HY-19642AGlesatinib hydrochloride -
Similarity Score 0.67
HY-123225LCRF-0004 -
Similarity Score 0.62
HY-12423Pamufetinib -
Similarity Score 0.59
HY-12423APamufetinib mesylate -
Similarity Score 0.57
HY-16961Sitravatinib -
Similarity Score 0.53
HY-16961ASitravatinib malate -
Similarity Score 0.52
HY-155812Tyrosine kinase-IN-6 -
Similarity Score 0.51
HY-116721AG-28262 -
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