1 Result for "

MGS0039

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MGS0039" in MCE Product Catalog:

Art. -Nr.: HY-123411
CAS. Nr.: 569686-87-9
Synonyms: BCI 632
Target:  

mGluR

Forschungsgebiete:  

Neurological Disease

MGS0039 is a type II group mGluR antagonist. MGS0039 has a high affinity for mGluR2 and mGluR3, with Ki values of 2.2 nM and 4.5 nM, respectively. MGS0039 can attenuate the inhibitory effect of glutamate-induced cyclic AMP formation triggered by Forskolin (HY-15371) in CHO cells expressing mGluR2/mGluR3. MGS0039 shows antidepressant-like activity in rats .
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