1 Result for "

MK0731

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MK0731" in MCE Product Catalog:

Cat. No.: HY-50672
CAS No.: 845256-65-7
Research Areas:  

Cancer

MK-0731 is a selective, non-competitive and allosteric kinesin spindle protein (KSP) inhibitor with an IC50 of 2.2 nM and a pKa of 7.6. MK-0731 is >20,000 fold selectivity against other kinesins. MK-0731 induces mitotic arrest and induces apoptosis in tumors. MK-0731 provides significant antitumor efficacy .
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