1 Result for "

MK1088

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MK1088" in MCE Product Catalog:

Cat. No.: HY-183599
CAS No.: 2433765-51-4
Target:  

Adenosine Receptor

Research Areas:  

Cancer

MK-1088 is an orally active A2A/A2B adenosine receptor antagonist with human A2A Ki of 0.31 nM, human A2B Ki 5.3 nM. MK-1088 blocks receptor downstream signaling, inhibits CREB phosphorylation and reverses adenosine-mediated immunosuppression. MK-1088 restores TNF−α release and enhances tumor immune surveillance. MK-1088 can be used for the research of cancer[1].
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