2 Results for "

MKN74

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "MKN74" in MCE Product Catalog:

Cat. No.: HY-150026
CAS No.: 2095628-21-8
Research Areas:  

Cancer

Multi-kinase-IN-2 (compound 7h) is an orally active and potent angiokinase inhibitor. Multi-kinase-IN-2 exhibits excellent inhibitory activity against angiokinases including VEGFR-1/2/3, PDGFRα/β, and FGFR-1, as well as LYN and c-KIT kinases. Multi-kinase-IN-2 significantly attenuates phosphorylation of AKT and ERK proteins. Multi-kinase-IN-2 induces cell apoptosis. Multi-kinase-IN-2 shows anticancer activity .
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Cat. No.: HY-150027
CAS No.: 2091950-43-3
Target:  

VEGFR PDGFR

Research Areas:  

Cancer

Multi-kinase-IN-3 (compound 2) is a potent angiokinase inhibitor. Multi-kinase-IN-3 shows inhibition activity against VEGFR-2 and PDGFRβ, with IC50 values of 58.3 and 55 nM, respectively .
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