2091950-43-3
2091950-43-3
Chemical Structure
Multi-kinase-IN-3
- CAS No.: 2091950-43-3
- Formula:C33H33N5O3
- Molecular Weight:547.65
IUPAC Name: methyl (Z)-3-(((4-(2-((4-methylpiperazin-1-yl)methyl)-1H-pyrrol-1-yl)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate
InChIKey: XIYGJVNJPZOWAE-KTMFPKCZSA-N
SMILES: O=C(C1=CC(NC/2=O)=C(C=C1)C2=C(NC3=CC=C(N4C=CC=C4CN5CCN(C)CC5)C=C3)/C6=CC=CC=C6)OC
Biological Activity: Multi-kinase-IN-3 (compound 2) is a potent angiokinase inhibitor. Multi-kinase-IN-3 shows inhibition activity against VEGFR-2 and PDGFRβ, with IC50 values of 58.3 and 55 nM, respectively[1].
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Multi-kinase-IN-3 | Multi-kinase-IN-3 (compound 2) is a potent angiokinase inhibitor. Multi-kinase-IN-3 shows inhibition activity against VEGFR-2 and PDGFRβ, with IC50 values of 58.3 and 55 nM, respectively. | |||||||||||||||||||||
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References
Keywords
