1. Protein Tyrosine Kinase/RTK
  2. VEGFR PDGFR
  3. Multi-kinase-IN-3

Multi-kinase-IN-3 (compound 2) is a potent angiokinase inhibitor. Multi-kinase-IN-3 shows inhibition activity against VEGFR-2 and PDGFRβ, with IC50 values of 58.3 and 55 nM, respectively.

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Multi-kinase-IN-3 Chemical Structure

Multi-kinase-IN-3 Chemical Structure

CAS No. : 2091950-43-3

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Description

Multi-kinase-IN-3 (compound 2) is a potent angiokinase inhibitor. Multi-kinase-IN-3 shows inhibition activity against VEGFR-2 and PDGFRβ, with IC50 values of 58.3 and 55 nM, respectively[1].

IC50 & Target

PDGFRβ

55 ± 2.6 nM (IC50)

VEGFR-2

58.3 ± 5.9 nM (IC50)

Molecular Weight

547.65

Formula

C33H33N5O3

CAS No.
SMILES

O=C(C1=CC(NC/2=O)=C(C=C1)C2=C(NC3=CC=C(N4C=CC=C4CN5CCN(C)CC5)C=C3)/C6=CC=CC=C6)OC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Multi-kinase-IN-3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Multi-kinase-IN-3
Cat. No.:
HY-150027
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