1 Result for "

MM473

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "MM473" in MCE Product Catalog:

Cat. No.: HY-143411
CAS No.: 2487526-28-1
Research Areas:  

Cancer

GEM144 is a potent and orally active DNA polymerase α (POLA1) and HDAC 11 dual inhibitor. GEM144 induces acetylation of p53, activation of p21, G1/S cell cycle arrest, and apoptosis. GEM144 has significant antitumor activity in human orthotopic malignant pleural mesothelioma xenografts .
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