1 Result for "

MODAG005

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "MODAG005" in MCE Product Catalog:

Cat. No.: HY-184511
CAS No.: 2648041-73-8
Research Areas:  

Neurological Disease

MODAG-005 is a blood-brain barrier-permeable PET probe precursor for α-synuclein (α‑Syn) aggregates, with a Ki value of 0.4 nM and a Kd value of 0.2 nM. MODAG-005 specifically binds to high-affinity sites within the tubular cavity of α-synuclein fibrils, and exhibits selectivity over tau protein fibrils and β-amyloid (A1-42) fibrils. MODAG-005 is applicable to the research of multiple system atrophy and Parkinson's disease .
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