1 Result for "

MR16728

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MR16728" in MCE Product Catalog:

Cat. No.: HY-100981
CAS No.: 207403-36-9
Target:  

Endogenous Metabolite

Research Areas:  

Neurological Disease

MR-16728 hydrochloride is a compound that promotes the release of acetylcholine and has activity that enhances the release of acetylcholine. MR-16728 hydrochloride inhibits acetylcholine release induced by KCl depolarization. MR-16728 hydrochloride also inhibits Ca(2+)-ATPase activity in pure presynaptic membranes. The half-maximal effect of MR-16728 hydrochloride occurs at a concentration of 13.5 μM. MR-16728 hydrochloride significantly enhances the release of acetylcholine in the presence of low concentrations of calcium (approximately 10 μM range). Enhanced acetylcholine release was also observed with MR-16728 hydrochloride in proteoliposomes loaded with mediator proteins .
loading...
    loading...