1 Result for "

MRSA DN65

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "MRSA DN65" in MCE Product Catalog:

3-WP
3-WP
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製品番号: HY-P11909
Target:  

Bacterial Reactive Oxygen Species (ROS)

研究分野:  

Infection

3-WP is a linear 20-peptide with a C-terminal amidation modification. 3-WP acts on lipoteichoic acid (LTA) and disrupts cell wall permeability, induces intracellular reactive oxygen species (ROS) accumulation in a dose-dependent manner, and simultaneously inhibits respiratory chain dehydrogenase activity and intracellular ATP synthesis, thereby interfering with bacterial energy metabolism and exerting Bacterial antibacterial effects. The combination of 3-WP and Melittin (HY-P0233) exerts synergistic antibacterial effects against Gram-positive bacteria, reduces the required dosage of Melittin, and thus improves the cell selectivity of Melittin. 3-WP can serve as a peptide adjuvant for Melittin in food storage scenarios. 3-WP can be used in the research of foodborne diseases caused by methicillin-resistant Staphylococcus aureus .
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