1 Result for "

MRT92

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "MRT92" in MCE Product Catalog:

Cat. No.: HY-117903A
CAS No.: 1428315-82-5
Target:  

Smo Hedgehog

Research Areas:  

Cancer

MRT-92 is a Smoothened (Smo) antagonist (Ki=0.7 nM) with anticancer activity. MRT-92 inhibits Hedgehog signaling pathway and rodent cerebellar granule cell proliferation by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor (IC50=0.4 nM). MRT-92 can be used in the study of cerebellar glioma .
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