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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
MS177
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "MS177" in MCE Product Catalog:
3
3 Cited Publications
Research Areas:
MS177 is an effective and fast-acting EZH2 degrader. MS177 is a PROTAC that consists of a CRBN ligand, linker, and a potent enzymatic EZH2 inhibitor C24 (C24 IC50): 12 nM). MS177 effectively depletes both canonical EZH2-PRC2 and noncanonical EZH2-cMyc complexes. MS177 induces leukaemia cell growth inhibition, apoptosis and cell cycle progression arrest .
Cat. No.: HY-W1063360
CAS No.: 2225940-27-0
Research Areas:
EZH2 ligand-5 is an EZH2 ligand. EZH2 ligand-5 serves as a ligand for the target protein in the synthesis of PROTAC EZH2 degraders, such as MS177 (HY-148333). EZH2 ligand-5 can be used in leukemia research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
