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Referencia número: HY-W1063360

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EZH2 ligand-5

EZH2 ligand-5 is an EZH2 ligand. EZH2 ligand-5 serves as a ligand for the target protein in the synthesis of PROTAC EZH2 degraders, such as MS177 (HY-148333). EZH2 ligand-5 can be used in leukemia research.

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No. CAS: 2225940-27-0
Fòrmula: C₃₀H₃₈N₈O₂
Peso molecular:542.68

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

EZH2 ligand-5 Chemical Structure

No. CAS: 2225940-27-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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IC₅₀ & Target^[1]

EZH2

Ver todos los productos específicos de isoformas Histone Methyltransferase :

Chemical Information

No. CAS 2225940-27-0
Peso molecular 542.68
Fòrmula C₃₀H₃₈N₈O₂
SMILES

O=C(C1=CC(C2=CC=C(N3CCN(CCN)CC3)N=C2)=CC4=C1C=NN4C(C)C)NCC5=C(C)C=C(C)NC5=O
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Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Wang J, et al. EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis. Nat Cell Biol. 2022 Mar;24(3):384-399. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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EZH2 ligand-5

Ver todos los productos específicos de isoformas Histone Methyltransferase

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

EZH2 ligand-5 Related Classifications

HY-W1063360 Related Classifications