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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
MTI-446
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "MTI-446" in MCE Product Catalog:
4
Target:
Research Areas:
Dinotefuran is an orally active and competitive inhibitor and insecticide targeting insect nicotinic acetylcholine receptors (nAChRs). Dinotefuran blocks neural signaling and induces neural dysfunction in insects. Dinotefuran binds to [ 3H]epibatidine in the neural cord membrane of American cockroach with an IC50 of 890 nM and to [ 3H]α-bungarotoxin with an IC50 of 36.1 μM. Dinotefuran exhibits knockdown activity (KD50=0.351 nmol/g) and lethal activity (LD50=0.173 nmol/g) against German cockroach. Dinotefuran is mainly used for agricultural pest control, such as field control of piercing-sucking and chewing insects (e.g., aphids, planthoppers), while its environmental toxicological effects (e.g., oxidative stress and reproductive neurotoxicity on earthworms) are also a research focus to assess ecological risks .
Cat. No.: HY-B0827R
CAS No.: 165252-70-0
Synonyms: MTI-446 (Standard)
Target:
Research Areas:
Dinotefuran (Standard) is the analytical standard of Dinotefuran. This product is intended for research and analytical applications.
Cat. No.: HY-B0827S
CAS No.: 2934813-27-9
Synonyms: MTI-446-d3
Cat. No.: HY-B0827B
CAS No.: 322639-07-6
Synonyms: (S)-MTI-446
(S)-Dinotefuran ((S)-MTI-446), a neonicotinoid pesticide, is toxic by binding to α8 subunit of nAChR of honeybee Apis mellifera (Apis mellifera Linnaeus). (S)-Dinotefuran shows more toxic than R-dinotefuran to honeybee Apis mellifera .
Cat. No.: HY-B0827A
CAS No.: 406466-53-3
Synonyms: (R)-MTI-446
(R)-Dinotefuran ((R)-MTI-446), a neonicotinoid pesticide, exhibits comparative insecticidal activities (1.7-2.4 times) to typical sucking pests Aphis gossypii and Apolygus lucorum compared to racemic mixtures by inhibiting nicotinic acetylcholine receptors. (R)-Dinotefuran has a good efficacy in controlling target pests while minimizing hazard to honeybees .
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Protocols
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