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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
Michael acceptors
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "Michael acceptors" in MCE Product Catalog:
8
8 Cited Publications
RR-11a analog is a potent and irreversible inhibitor of Schistosoma mansoni legumain, with an IC50 of 31 nM. RR-11a analog is an aza-Asn derivative and aza-peptide Michael acceptor .
Cat. No.: HY-N2240
CAS No.: 108657-10-9
Category:
Melilotus albus Desr. Terpenoids Sesquiterpenes Plants Compositae Disease Research Fields Cancer
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Cat. No.: HY-P10828
CAS No.: 1260620-30-1
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Cat. No.: HY-W800833
CAS No.: 55946-27-5
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Research Areas:
Benzyl N-[2-(prop-2-enamido)ethyl]carbamate is a short aliphatic linker featuring a Cbz-protected amine and an acrylamide. Acrylamide is a Michael acceptor which is a good Michael acceptor which can be used in thiol-based bioconjugation or polymerization. Meanwhile, the Cbz protecting group can be removed using Pd-C hydrogenation to reveal a free amine that can participate in a wide variety of reactions such as couplings or reductive amination.
Cat. No.: HY-N20659
CAS No.: 1376654-34-0
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Cat. No.: HY-W392912A
CAS No.: 2833-24-1
Synonyms: Methyl (2E)-4-oxopent-2-enoate
Research Areas:
Methyl trans-4-oxo-2-pentenoate (Methyl (2E)-4-oxopent-2-enoate) is a heterofunctionalized dienophile containing both ketone and ester functional groups. The enone structure within the Methyl trans-4-oxo-2-pentenoate molecule makes it a highly reactive Michael acceptor capable of regioselective conjugate addition, which is commonly used in reactions for constructing complex ring systems such as the Robinson annulation. Methyl trans-4-oxo-2-pentenoate can serve as a substrate in the synthesis of α-(alkylmethylene) butyrolactone derivatives. Methyl trans-4-oxo-2-pentenoate participates in asymmetric Diels-Alder reactions promoted by chiral palladium complexes .
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Protocols
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