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Isoforms Recommended: Kinesin-6
Results for "

Mklp2

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-101298
    Paprotrain
    4 Publications Verification

    Kinesin Neurological Disease
    Paprotrain is a cell-permeable inhibitor of the kinesin MKLP-2, inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM and shows a moderate inhibition activity on DYRK1A with an IC50 of 5.5 μM.
    Paprotrain
  • HY-RS07272

    Small Interfering RNA (siRNA) Others

    KIF20A Human Pre-designed siRNA Set A contains three designed siRNAs for KIF20A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    KIF20A Human Pre-designed siRNA Set A
    KIF20A Human Pre-designed siRNA Set A
  • HY-170850

    Kinesin Cancer
    MKLP2-IN-1 (compound 12a) is an inhibitor of MKLP2 with good oral bioavailability. MKLP2-IN-1 inhibits the microtubule-stimulated ATPase activity of recombinant MKLP2 in vitro and suppresses tumor growth in a mouse Calu-6 lung cancer model .
    MKLP2-IN-1
  • HY-161112

    Kinesin Others
    LG157 is a potent inhibitor of mitotic kinesin-like protein 2 (MKLP2) .
    LG157
  • HY-101298R

    Kinesin Reference Standards Neurological Disease
    Paprotrain (Standard) is the analytical standard of Paprotrain (HY-101298). This product is intended for research and analytical applications. Paprotrain is a cell-permeable inhibitor of the kinesin MKLP-2, inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM and shows a moderate inhibition activity on DYRK1A with an IC50 of 5.5 μM.
    Paprotrain (Standard)
  • HY-104023

    Polo-like Kinase (PLK) Cancer
    ZK-Thiazolidinone is an ATP-competitive Polo-like kinase 1 (Plk1) inhibitor with an IC50 of 19 nM. ZK-Thiazolidinone inhibits tumor cell proliferation, induces cell cycle arrest and typical mitotic defects. ZK-Thiazolidinone impairs the recruitment of γ-tubulin and Aurora A kinase to centrosomes, resulting in failure of bipolar spindle maintenance and sister chromatid arm cohesion.\nZK-Thiazolidinone is applicable for cancer research .
    ZK-Thiazolidinone

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