57046-73-8
57046-73-8
Chemical Structure
Paprotrain
- CAS No.: 57046-73-8
- Formula:C16H11N3
- Molecular Weight:245.28
IUPAC Name: (Z)-2-(1H-indol-3-yl)-3-(pyridin-3-yl)acrylonitrile
InChIKey: YMYYQRZCCKBFBE-MDWZMJQESA-N
SMILES: N#C/C(C1=CNC2=CC=CC=C21)=C\C3=CN=CC=C3
Biological Activity: Paprotrain is a cell-permeable inhibitor of the kinesin MKLP-2, inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM and shows a moderate inhibition activity on DYRK1A with an IC50 of 5.5 μM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Paprotrain | 99.85% | Paprotrain is a cell-permeable inhibitor of the kinesin MKLP-2, inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM and shows a moderate inhibition activity on DYRK1A with an IC50 of 5.5 μM. | ||||||||||||||||||||
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Paprotrain (Standard) | ≥98% | Paprotrain (Standard) is the analytical standard of Paprotrain (HY-101298). This product is intended for research and analytical applications. Paprotrain is a cell-permeable inhibitor of the kinesin MKLP-2, inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM and shows a moderate inhibition activity on DYRK1A with an IC50 of 5.5 μM. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.75
HY-136310PIP4K-IN-a131 -
Similarity Score 0.69
HY-108681R680C91 (Standard) -
Similarity Score 0.67
HY-100395RF16 (Standard) -
Similarity Score 0.66
HY-137394Nicotredole -
Similarity Score 0.64
HY-156348MAO-B-IN-26 -
Similarity Score 0.64
HY-W287494Antitumor agent-202 -
Similarity Score 0.64
HY-1588142-(2-Chlorophenyl)-1-(1H-indol-3-yl)ethanone -
Similarity Score 0.63
HY-101426RG14620 -
Similarity Score 0.63
HY-161601Ferroptosis inducer-2 -
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