2 Results for "

NC-002

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "NC-002" in MCE Product Catalog:

Cat. No.: HY-P11311
CAS No.: 1356828-46-0
Target:  

Proteasome

Research Areas:  

Cancer

NC-002, a cell-permeable peptide, is a Trypsin-like proteasome inhibitor without inhibition of lysosomal cysteine proteases. NC-002 is the epoxyketone derivative of Leupeptin (HY-18234). NC-002 sensitizes myeloma cells to Bortezomib (HY-10227) and Carfilzomib (HY-10455). NC-002 can be used for cancers research .
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Cat. No.: HY-P11331
CAS No.: 1356828-49-3
Target:  

Proteasome

Research Areas:  

Others

Az-NC-002 is a Proteasome trypsin-like site (β2) and immunoproteasome β2i-specific active probe. Az-NC-002 has weak off-target effects with no significant inhibition for Cathepsin D (HY-P2750), but this inhibition reacts outside of the active site or influence on a small fraction of the enzyme .
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