1356828-46-0
1356828-46-0
Chemical Structure
NC-002
- CAS No.: 1356828-46-0
- Formula:C23H42N6O5
- Molecular Weight:482.62
SMILES: CC(C)C[C@H](NC(C)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C([C@]1(CO1)C)=O)=O)=O
Biological Activity: NC-002, a cell-permeable peptide, is a Trypsin-like proteasome inhibitor without inhibition of lysosomal cysteine proteases. NC-002 is the epoxyketone derivative of Leupeptin (HY-18234). NC-002 sensitizes myeloma cells to Bortezomib (HY-10227) and Carfilzomib (HY-10455). NC-002 can be used for cancers research[1].
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NC-002 | NC-002, a cell-permeable peptide, is a Trypsin-like proteasome inhibitor without inhibition of lysosomal cysteine proteases. NC-002 is the epoxyketone derivative of Leupeptin (HY-18234). NC-002 sensitizes myeloma cells to Bortezomib (HY-10227) and Carfilzomib (HY-10455). NC-002 can be used for cancers research. | |||||||||||||||||||||
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References
Keywords
