1 Result for "

NC762

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NC762" in MCE Product Catalog:

Cat. No.: HY-P991223

Research Areas:  

Cancer

NC762 is a humanized IgG1κ monoclonal antibody that targets human B7-H4 (B7 homolog 4). NC762 has enhanced binding to CD16a (FcγRIIIa) after being Fc engineered with three point mutations (S239D/A330L/I332E; DLE) and demonstrate increased antibody-dependent cellular cytotoxicity (ADCC) activity. NC762 inhibits tumor growth in vivo through binding to tumor-expressing B7-H4. NC762 can be studies in research on cancer such as advanced or metastatic solid tumors .
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