1 Result for "

NCT58

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NCT58" in MCE Product Catalog:

Cat. No.: HY-145102
CAS No.: 2411429-33-7
Purity:  99.63%
Target:  

HSP Apoptosis

Research Areas:  

Cancer

NCT-58 is a potent inhibitor of C-terminal HSP90. NCT-58 does not induce the heat shock response (HSR) due to its targeting of the C-terminal region and elicits anti-tumor activity via the simultaneous downregulation of HER family members as well as inhibition of Akt phosphorylation. NCT-58 kills Trastuzumab-resistant breast cancer stem-like cells. NCT-58 induces apoptosis in HER2-positive breast cancer cells .
loading...
    loading...