1 Result for "

NHI2

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NHI2" in MCE Product Catalog:

Cat. No.: HY-124309
CAS No.: 1269802-97-2
Purity:  99.30%
Research Areas:  

Cancer

NHI-2 is a lactate dehydrogenase A (LDHA) inhibitor with an IC50 of 14.7 µM. NHI-2 shows selective for LDHA over LDHB (IC50 = 55.8 µM). NHI-2 is an efficient anti-glycolytic agent. NHI-2 enhances apoptosis, induces cell cycle arrest at S and G2 phases. NHI-2 has a broad spectrum anti-proliferative activity in cancer cells. NHI-2 affects extracellular acidification rate and ATP production. NHI-2 suppresses tumor growth in murine B78 melanoma tumor model [2].
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