2. Metabolic Enzyme/Protease
  3. Lactate Dehydrogenase
  4. NHI-2

NHI-2 is a potent inhibitor of LDH-A. NHI-2 is an efficient anti-glycolytic agent. NHI-2 has the potential for the research of cancer disease.

For research use only. We do not sell to patients.

NHI-2 Chemical Structure

NHI-2 Chemical Structure

CAS No. : 1269802-97-2

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Based on 1 publication(s) in Google Scholar

NHI-2 Related Antibodies

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Description

NHI-2 is a potent inhibitor of LDH-A. NHI-2 is an efficient anti-glycolytic agent. NHI-2 has the potential for the research of cancer disease[1].

Molecular Weight

335.28

Formula

C17H12F3NO3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

ON1C2=CC(C3=CC=CC=C3)=CC(C(F)(F)F)=C2C=C1C(OC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (74.56 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9826 mL 14.9129 mL 29.8258 mL
5 mM 0.5965 mL 2.9826 mL 5.9652 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.30%

COA (250 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9826 mL 14.9129 mL 29.8258 mL 74.5645 mL
5 mM 0.5965 mL 2.9826 mL 5.9652 mL 14.9129 mL
10 mM 0.2983 mL 1.4913 mL 2.9826 mL 7.4565 mL
15 mM 0.1988 mL 0.9942 mL 1.9884 mL 4.9710 mL
20 mM 0.1491 mL 0.7456 mL 1.4913 mL 3.7282 mL
25 mM 0.1193 mL 0.5965 mL 1.1930 mL 2.9826 mL
30 mM 0.0994 mL 0.4971 mL 0.9942 mL 2.4855 mL
40 mM 0.0746 mL 0.3728 mL 0.7456 mL 1.8641 mL
50 mM 0.0597 mL 0.2983 mL 0.5965 mL 1.4913 mL
60 mM 0.0497 mL 0.2485 mL 0.4971 mL 1.2427 mL
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NHI-2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NHI-21269802-97-2NHI2NHI 2Lactate DehydrogenaseLDHLDH-Aanti-glycolyticcancerInhibitorinhibitorinhibit

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