1 Result for "

NHWL-071065

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "NHWL-071065" in MCE Product Catalog:

Cat. No.: HY-182797
CAS No.: 3117340-01-6
Research Areas:  

Cancer

NHWL071065 is a CRBN-targeting IKZF1/IKZF3 molecular glues degrader. NHWL071065 selectively degrades IKZF1 and IKZF3 in lymphoma cells via the ubiquitin-proteasome pathway. NHWL071065 inhibits the proliferation of lymphoma cells. NHWL071065 downregulates proteins involved in cytoskeleton assembly, cell adhesion and immune regulation in cells, while upregulating proteins related to the type I IFN signaling pathway. NHWL071065 can be used in the research of lymphoma .
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