3 Results for "

NOD/SCID mouse

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "NOD/SCID mouse" in MCE Product Catalog:

Cat. No.: HY-158776
CAS No.: 2755451-45-5
Target:  

Parasite

Research Areas:  

Infection

SLU-10482 is an orally active anti-parasitic agent, that inhibits Cryptosporidium parvum with an IC50 of 0.0687 μM. SLU-10482 exhibits anti-infective efficacy in C. parvum infected mice with an AC50 of 0.0686 μM .
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Cat. No.: HY-118912
CAS No.: 457937-39-2
BMH-9 (Compound Z54) is a modulator for nuclear receptor subfamily 2, group F, member 6 (NR2F6) (also known as nuclear orphan receptor Ear2) . BMH-9 is an activator for p53 signaling pathway through interaction with DNA. BMH-9 inhibits proliferation of human cancer cells, exhibits antitumor efficacy in NOD-SCID mouse models .
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Cat. No.: HY-181821
Target:  

Parasite Na+/K+ ATPase

Research Areas:  

Infection

MMV1581361 is a PfATP4 inhibitor and an orally active, transmission-blocking agent with nanomolar activity against Plasmodium falciparum blood-stage isolates. MMV1581361 disrupts sodium ion (Na +) homeostasis in Plasmodium falciparum. MMV1581361 inhibits male gamete exflagellation, reduces oocyst intensity, and blocks transmission of Plasmodium falciparum. MMV1581361 demonstrates efficacy in the humanized Plasmodium falciparum NOD scid IL2Rγ null mouse model. MMV1581361 can be used for the research of malaria .
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