457937-39-2
457937-39-2
Chemical Structure
BMH-9
- CAS No.: 457937-39-2
- Formula:C19H27N3O2
- Molecular Weight:329.44
IUPAC Name: ethyl 4-((3-(dimethylamino)propyl)amino)-6,8-dimethylquinoline-3-carboxylate
InChIKey: DRDAFDJAYXZMJW-UHFFFAOYSA-N
SMILES: O=C(OCC)C1=C(C2=CC(C)=CC(C)=C2N=C1)NCCCN(C)C
Biological Activity: BMH-9 (Compound Z54) is a modulator for nuclear receptor subfamily 2, group F, member 6 (NR2F6) (also known as nuclear orphan receptor Ear2)[1]. BMH-9 is an activator for p53 signaling pathway through interaction with DNA. BMH-9 inhibits proliferation of human cancer cells, exhibits antitumor efficacy in NOD-SCID mouse models[1].
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BMH-9 | BMH-9 (Compound Z54) is a modulator for nuclear receptor subfamily 2, group F, member 6 (NR2F6) (also known as nuclear orphan receptor Ear2). BMH-9 is an activator for p53 signaling pathway through interaction with DNA. BMH-9 inhibits proliferation of human cancer cells, exhibits antitumor efficacy in NOD-SCID mouse models. | |||||||||||||||||||||
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