Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
NOR1
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "NOR1" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-N6641
CAS No.: 21516-68-7
Category:
Natural Products other families Microorganisms Pigments Plants Disease Research Fields Inflammation/Immunology Food Research
Target:
Cat. No.: HY-W270810
CAS No.: 360778-55-8
Target:
Research Areas:
NR4A agonist-1, a fatty acid mimetic (FAM), is a potent NR4A agonist. NR4A agonist-1 exhibits high agonist potency on NR4A receptors Nurr1, Nur77, and NOR-1, with EC50s of 0.09 μM, 0.04 μM, and 0.15 μM, respectively [1].
Cat. No.: HY-N7041
Cat. No.: HY-N11009
CAS No.: 942612-74-0
Category:
Triterpenes Terpenoids Cucurbitaceae Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants
Target:
Cat. No.: HY-168809
CAS No.: 21420-59-7
Target:
Research Areas:
Norbaeocystin is an intermediate/minor metabolite naturally present in the psilocybin biosynthetic pathway of hallucinogenic mushrooms (Psilocybe spp.). Norbaeocystin has weak or no affinity for the serotonin 2A (5-HT2A) receptor and does not induce receptor activation. Norbaeocystin is rapidly metabolized by monoamine oxidase, and thus does not participate in centrally mediated psychedelic effects. Norbaeocystin can be used for studies on biological pathways associated with hallucinogenic effects [1] .
Cat. No.: HY-N7040
CAS No.: 2170761-38-1
Category:
Infection Triterpenes Terpenoids Cucurbitaceae Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Disease Research Fields
Target:
Cat. No.: HY-N9752
CAS No.: 942615-25-0
Category:
Cucurbitaceae Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Steroids
Target:
Cat. No.: HY-RS09552
Target:
Research Areas:
NR4A3 Human Pre-designed siRNA Set A contains three designed siRNAs for NR4A3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N8041
CAS No.: 88901-43-3
Category:
Infection Triterpenes Terpenoids Cucurbitaceae Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Disease Research Fields
Target:
Cat. No.: HY-N6641R
CAS No.: 21516-68-7
Category:
Target:
Cat. No.: HY-181588
Target:
Research Areas:
NR4A agonist-2 is a selective pan-NR4A agonist designed based on Vidofludimus (HY-14908), with a Kd of 0.10 μM against NR4A1, and EC50 values of 0.098 μM, 0.092 μM and 0.09 μM against Nur77, Nurr1, NOR-1, respectively. NR4A agonist-2 exhibits 47-fold selectivity over DHODH, and shows no cytotoxic activity at concentrations up to 10 μM. By binding to a specific surface pocket in the ligand-binding domain of Nurr1, NR4A agonist-2 inhibits the formation of Nurr1 homodimers, activates response elements such as NBRE, NurRE, DR5, and then potently induces the expression of neuroprotective genes including BDNF, SOD2, thereby exerting neuroprotective activity. NR4A agonist-2 can be used in the research of neurodegenerative diseases such as Parkinson's disease, dementia and multiple sclerosis [1].
Cat. No.: HY-15364
CAS No.: 130447-37-9
Target:
Research Areas:
19-nor-1α,25-Dihydroxyvitamin D3 is a vitamin D receptor (VDR) agonist with an EC50 of 4.8 nM. 19-nor-1α,25-Dihydroxyvitamin D3 binds to VDR and promotes gene transcription. 19-nor-1α,25-Dihydroxyvitamin D3 can be used in the research of diseases related to the vitamin D signaling pathway [1].
Cat. No.: HY-RS18292
Target:
Research Areas:
Nr4a3 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nr4a3 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18201
Target:
Research Areas:
Plscr1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Plscr1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-N17638
CAS No.: 942612-72-8
Category:
Cucurbitaceae Siraitia grosvenorii (Swingle) C. Jeffrey ex Lu et Z. Y. Zhang Plants Steroids
Target:
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
