3 Results for "

NSC330507

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "NSC330507" in MCE Product Catalog:

70
70 Cited Publications
Cat. No.: HY-10211
CAS No.: 75747-14-7
Purity:  99.01%
Synonyms: 17-AAG; NSC 330507; CP 127374
Tanespimycin (17-AAG) is a potent HSP90 inhibitor with an IC50 of 5 nM, having a 100-fold higher binding affinity for tumour cell derived HSP90 than normal cell derived HSP90 . Tanespimycin depletes cellular STK38/NDR1 and reduces STK38 kinase activity. Tanespimycin also downregulates the stk38 gene expression .
loading...
    loading...
Cat. No.: HY-10211R
CAS No.: 75747-14-7
Synonyms: 17-AAG (Standard); NSC 330507 (Standard); CP 127374 (Standard)
Tanespimycin (Standard) is the analytical standard of Tanespimycin. This product is intended for research and analytical applications. Tanespimycin (17-AAG) is a potent HSP90 inhibitor with an IC50 of 5 nM, having a 100-fold higher binding affinity for tumour cell derived HSP90 than normal cell derived HSP90 . Tanespimycin depletes cellular STK38/NDR1 and reduces STK38 kinase activity. Tanespimycin also downregulates the stk38 gene expression .
loading...
    loading...
Cat. No.: HY-10211S
Synonyms: 17-AAG-d5; NSC 330507-d5; CP 127374-d5
Tanespimycin-d5 (17-AAG-d5; NSC 330507-d5; CP 127374-d5) is the deuterium labeled Tanespimycin (HY-10211). Tanespimycin (17-AAG) is a potent HSP90 inhibitor with an IC50 of 5 nM, having a 100-fold higher binding affinity for tumour cell derived HSP90 than normal cell derived HSP90 . Tanespimycin depletes cellular STK38/NDR1 and reduces STK38 kinase activity. Tanespimycin also downregulates the stk38 gene expression .
loading...
    loading...