1 Result for "

NSD3-SET

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "NSD3-SET" in MCE Product Catalog:

Cat. No.: HY-162308
CAS No.: 744260-15-9
Research Areas:  

Cancer

NSD-IN-3 (compound 3) is a potent nuclear receptor binding SET domain (NSD) inhibitor. NSD-IN-3 inhibits NSD2-SET and NSD3-SET with IC50 values of 0.81 μM and 0.84 μM, respectively. NSD-IN-3 inhibits histone H3K36 dimethylation and decreases the expression of NSDs-targeted genes in non-small cell lung cancer cells. NSD-IN-3 induces s-phase cell cycle arrest and apoptosis .
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