10 Results for "

NaPi2

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "NaPi2" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P99229
CAS No.: 2254118-43-7
Synonyms: XMT-1535; Upinitatug

Target:  

ADC Antibodies

Research Areas:  

Cancer

Upifitamab is a humanized monoclonal antibody targeting NaPi2b. Upifitamab can be used to synthesize ADC such as Upfitamab rilsodotin. Upfitamab rilsodotin can be used in research for solid tumors including high-grade serious epithelial ovarian, fallopian tube and primary peritoneal cancer (OC). Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-112065
CAS No.: 2227425-05-8
Purity:  99.88%
Target:  

Sodium Channel

Research Areas:  

Metabolic Disease

PF-06869206 is an orally bioavailable selective inhibitor of the sodium-phosphate cotransporter NaPi2a (SLC34A1) with an IC50 of 380 nM .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-145894
CAS No.: 2227445-31-8
Purity:  98.93%
Target:  

Sodium Channel

Research Areas:  

Metabolic Disease

NaPi2b-IN-2 is a potent inhibitor of sodium-dependent phosphate transporter 2b (SLC34A2, NaPi2b), with an IC50 value of 38 nM against human NaPi2b. NaPi2b-IN-2 reduces intracellular phosphate levels and enhances innate immune gene expression. NaPi2b-IN-2 can be used in research related to hyperphosphatemia [2].
loading...
    loading...
Cat. No.: HY-P99970
CAS No.: 1615697-16-9

Research Areas:  

Cancer

Lifastuzumab is a humanized anti-NaPi2b IgG1 monoclonal antibody. Lifastuzumab can be coupled with monomethyl auristatin E (MMAE) (HY-15162) through ADC Linker to form an antibody-drug conjugate (ADC) Lifastuzumab vedotin (HY-P99705) with anticancer activity. Lifastuzumab vedotin can be studied in research for non-small cell lung cancer and ovarian cancer. Recommend Isotype Control: Human IgG1 kappa, Isotype Control (HY-P99001) [2].
loading...
    loading...
Cat. No.: HY-P99705
CAS No.: 1401812-88-1
Synonyms: RG-7599; DNIB-0600A; NaPi2b-ADC
Research Areas:  

Cancer

Lifastuzumab vedotin (RG-7599; DNIB0600A) is an antibody-drug conjugate (ADC) that comprises a humanized IgG1 anti-NaPi2b monoclonal antibody (MNIB2126A) and a potent antimitotic agent, monomethyl auristatin E (MMAE), which inhibits cell division by blocking the polymerization of tubulin. Lifastuzumab vedotin has the potential for non-small cell lung cancer (NSCLC) and platinum-resistant ovarian cancer (PROC) research .
loading...
    loading...
Cat. No.: HY-146429
CAS No.: 2227443-66-3
Target:  

Sodium Channel

Research Areas:  

Metabolic Disease

NaPi2b-IN-3 (compound 5) is a potent sodium-dependent transport protein 2b (SLC34A2, NaPi2b) inhibitor with IC50s of 71 nM and 28 nM for human NaPi2b and rat NaPi2b, respectively. NaPi2b-IN-3 can be used for researching hyperphosphatemia .
loading...
    loading...
Cat. No.: HY-142957
CAS No.: 1453116-06-7
Research Areas:  

Others

NaPi2b-IN-1 is a potent and orally active inhibitor of sodium-dependent phosphate transport protein 2b (NaPi2b) with an IC50 of 64 nM. NaPi2b is primarily expressed in the small intestine, lungs, and testes and plays an important role in phosphate homeostasis. NaPi2b-IN-1 has the potential for the research of hyperphosphatemia .
loading...
    loading...
Cat. No.: HY-P81437
Synonyms: SLC34A2; Sodium-dependent phosphate transport protein 2B; Sodium-phosphate transport protein 2B; Na(+)-dependent phosphate cotransporter 2B; NaPi3b; Sodium/phosphate cotransporter 2B (Na(+)/Pi cotransporter 2B; NaPi-2b); Solute carrier family 34 member 2

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

loading...
    loading...
Cat. No.: HY-P81437A
Synonyms: SLC34A2; Sodium-dependent phosphate transport protein 2B; Sodium-phosphate transport protein 2B; Na(+)-dependent phosphate cotransporter 2B; NaPi3b; Sodium/phosphate cotransporter 2B (Na(+)/Pi cotransporter 2B; NaPi-2b); Solute carrier family 34 member 2

Host:  

Rabbit

Application:  

IHC-P

Reactivity:  

Human

loading...
    loading...
Cat. No.: HY-P705898
Purity:  ≥ 90%, as determined by reducing SDS-PAGE
Synonyms: SLC34A3; Na(+)-Dependent Phosphate Cotransporter 2C; Solute Carrier Family 34 Member 3; Sodium-Phosphate Transport Protein 2C; Sodium-Dependent Phosphate Transport Protein 2C; Na(+)/Pi Cotransporter 2C; NaPi-2c; FLJ38680; NPT2C; Sodium/Phosphate Cotranspo
Species:  
Source:  
loading...
    loading...