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Neceprevir

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-108029

    ACH-2684 sodium; Neceprevir sodium

    HCV HCV Protease Infection
    Deldeprevir (ACH-2684; Neceprevir) sodium is a HCV NS3/4A protease inhibitor and resistance inhibitor. Deldeprevir sodium exhibits activity against wild-type genotype 1a and 1b HCV, including mutant strains resistant to other NS3 protease inhibitors. Deldeprevir sodium blocks the emergence of HCV mutant strains resistant to ACH-3422 in vitro, with enhanced efficacy when used in triple combination with ACH-3422 and ACH-3102 (HY-124182). Deldeprevir sodium shows additive antiviral potency when combined with ACH-3422, and exerts antiviral activity against HCV replicons carrying ACH-3102. Deldeprevir sodium is applicable to research related to hepatitis C .
    Deldeprevir sodium
  • HY-167293

    ACH-2684; Neceprevir

    HCV Protease Infection
    Deldeprevir (ACH-2684) is a HCV NS3 protease inhibitor. Deldeprevir has potent antiviral activities against different genotypes and against known resistant variants (such as R155, Al56 and D168) by the formation a highly stable complex with NS3 prolease. Deldeprevir can be used for Hepatitis C virus infection research .
    Deldeprevir

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