1 Result for "

OM137

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "OM137" in MCE Product Catalog:

Cat. No.: HY-123279
CAS No.: 292170-13-9
Target:  

Aurora Kinase CDK

Research Areas:  

Cancer

OM137 is an aurora kinase inhibitor, with an IC50 of 21.7 μM (Aurora A kinase) and 2.4 μM (Aurora B kinase). OM137 also inhibits Cdk1/cyclinB and Cdk5/p25 with an approximate IC50 of 20 μM. OM137 reduces spindle checkpoint-signaling proteins (Mad2 and BubR1) at the kinetochores of chromosomes .
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